DenpaNews While microbiology and biochemistry led to fundamental change a century ago, the current drivers are the emerging technologies of genomics, proteomics, and metabolomics, along with bioinformatics, medical informatics, biostatistics, data mining, and decision support sciences.
Prospective medicine refers to health services aimed at determining the risk of catching diseases, detecting the first onset of diseases and intervening early in treatment.
The primary focus of physicians in current diagnosis and treatment practices is the patient’s main complaint. For prospective diagnosis and treatment, a risk analysis based primarily on genetic, environmental and lifestyle assessments, further epidemiological and genomic research should be performed.
In the development of forward-looking medicine, genomic, proteomics and metabolomics technologies that emerged with the development of bioinformatics, medical informatics, biostatistics, data mining and decision support sciences gain importance.
Genomics, proteomics and metabolomics
genomics ; It examines the control of the interaction of these genes with each other and with the environment, identifying all the genes that encode the structural and functional functions of any organism.
Proteomics ; It illuminates the structures, locations, amounts, post-translational modifications, functions in tissues and cells, and interactions with other proteins and macromolecules of all proteins in a certain place at a certain time.
Metabolomics ; It is the detection, quantification and identification of small molecule metabolites emerging from lipids, carbohydrates, vitamins, hormones and other cell components in tissues, cells and physiological fluids in a certain time period using high-throughput technologies.
Genomics and proteomics give the information of “what could happen” and metabolomics “what actually happened”.
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Determining the risk of individuals developing certain diseases, detecting the earliest onset of disease, and responding or intervening early enough for maximum benefit is prospective health care based on the creation and validation of
Personalized Health Planning
Personalized health plans and the mechanisms to implement them are an essential component of prospective health care. Likewise, personal health planning should be undertaken to take preventive measures to minimize the possibilities of progression of chronic disease. The personalized health plan will include the person’s health profile, a description of their current health status, a health risk analysis (genetic, environmental, and lifestyle aspects), and countermeasures to be implemented over the course of a year.
Some have started pilot programs at their own institutions to promote prospective healthcare, and they are running different studies simultaneously to develop models for using genomic medicine.
Forward-looking healthcare: the second transformation of medicine
The most important component of the transition to prospective health care is the high estimation of disease risks. The development of new technologies will support the current ability to better diagnose and treat, as well as predict disease and appropriate interventions.
While microbiology and biochemistry led to fundamental change a century ago, the current drivers are the emerging technologies of genomics, proteomics, and metabolomics, along with bioinformatics, medical informatics, biostatistics, data mining, and decision support sciences.
With the identification of prospective healthcare-related components and personalized healthcare plan components, prospective medicine will usher in a new era in patient-centered healthcare.